Cardiac Rhabdomyomas and Congenital Hypothyroidism: A Coincidence or Hamartia
نویسنده
چکیده
Article type: Case Report Cardiac rhabdomyomas are the most common primary cardiac tumors in children. These tumors are generally asymptomatic, although they may be associated with neonatal tuberous sclerosis complex. Despite the fact that thyroid dysfunction rarely occurs in tuberous sclerosis, papillary adenomas (hamartomas) of the thyroid gland have been reported in a number of autopsies. Herein, we present the case of an infant with tuberous sclerosis, congenital hypothyroidism and multiple cardiac rhabdomyomas, leading to atrioventricular node dysfunction. Considering the rarity of this co-occurrence, we decided to report the present case. The co-occurrence of these two disorders in one patient may be a mere coincidence or related to hamartoma of the thyroid gland as a consequence of tuberous sclerosis gene products. Article history: Received: 26 Jul 2015 Revised: 20 Aug 2015 Accepted: 27 Oct 2015
منابع مشابه
Cardiac Rhabdomyomas and Congenital Hypothyroidism: A Coincidence or Hamartia
Cardiac rhabdomyomas are the most common primary cardiac tumors in children. These tumors are generally asymptomatic, although they may be associated with neonatal tuberous sclerosis complex. Despite the fact that thyroid dysfunction rarely occurs in tuberous sclerosis, papillary adenomas (hamartomas) of the thyroid gland have been reported in a number of autopsies. Herein, we present the case ...
متن کاملFrequency of Congenital Cardiac Malformations in the Neonates with Congenital Hypothyroidism
Background: Congenital hypothyroidism (CH) is a prevalent disorder, which is associated with several other congenital anomalies, especially cardiac diseases. The present study aimed to determine the prevalence of congenital heart disease (CHD) in the neonates with CH.Methods: This cross-sectional study was conducted on two groups of 79 subjects to compare the type and frequency of congenital ca...
متن کاملThe Importance of Examining Congenital Hypothyroidism in Connection with Congenital Heart Disease: Letter to Editor
Dear Editor-in-Chief: I read and enjoyed your stylish article, "Frequency of Congenital Cardiac Malformations in Neonates with Congenital Hypothyroidism", in relation to heart disease with hypothyroidism. As we know, one of the most commonly associated congenital hypothyroidism disorders is congenital heart disease, which has a significant effect on the recovery of pat...
متن کاملNerve Hamartomas - Fact or Fiction?
Hamartoma, derived from the Greek hamartia meaning “failure”, is a benign malformation composed of local native tissues with disorganized growth. Hamartomas are the most common benign tumors of the lung and the pediatric heart (cardiac rhabdomyomas), though they can be found throughout the body in most anatomical structures. Though typically benign ‘incidentalomas’, they can cause adjacent comp...
متن کاملEffect of Transient Congenital Hypothyroidism on Oxidative Stress in Cardiac Tissue of Adult Male Rats
Introduction: Increased oxidative stress is involved in the pathology of cardiovascular disease. Transient congenital hypothyroidism (TCH) leads to a variety of heart disorders during adulthood. In this study, the effect of TCH on antioxidant and oxidant systems in the serum and left cardiac ventricle of adult male rats was investigated. Materials and Methods: TCH was induced by administrating ...
متن کامل